human islet medium Search Results


90
Insphero Inc 3d insighttm human islet maintenance medium
3d Insighttm Human Islet Maintenance Medium, supplied by Insphero Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/3d insighttm human islet maintenance medium/product/Insphero Inc
Average 90 stars, based on 1 article reviews
3d insighttm human islet maintenance medium - by Bioz Stars, 2026-03
90/100 stars
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90
Insphero Inc human islet maintenance medium
( A ) Proliferation of islets in the diseased (11 mM glucose, 50 µM HCT) and healthy (5.5 mM glucose, 10 nM HCT) conditions at the end of the culture as analysed by the percentage EdU-positive cells. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies. Differences between the static and the co-culture were evaluated by a two-tailed unpaired t-test, ns = not significant, ****p < 0.0001. ( B ) Multi-omics analysis on the effect of hyperglycemia vs. normoglycemia on liver-secreted proteins. Data from RNASeq (HepaRG/HHSteC spheroids) and proteomics (co-culture supernatants) were merged at the gene level. Point colour indicate significance of change (FDR<0.05 and p<0.05 for RNASeq and proteomics data, respectively). Gene names are marked for genes with RNASeq and proteomic log2 fold-changes > 1. Transcriptomics data is from three independent studies and proteomics data from four independent studies. ( C ) Secretion of IL-1R2 in the co-cultures over time. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies, total n = 8. ( D ) IL-1R2 stimulates cell proliferation at low dose (0.3 ng/mL) but not at the high dose (30 ng/mL) in islets mono-cultured in static condition in <t>Human</t> <t>Islet</t> <t>Maintenance</t> <t>Medium</t> (InSphero). Control, 0 ng/mL IL-1R2. Positive control, low hydrocortisone-normoglycemic (healthy) co-culture medium. Symbols represent individual islets. Differences to the control were evaluated by one-way ANOVA using Dunnett’s multiple comparisons post-hoc test, ns = not significant, ***p < 0.001.
Human Islet Maintenance Medium, supplied by Insphero Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human islet maintenance medium/product/Insphero Inc
Average 90 stars, based on 1 article reviews
human islet maintenance medium - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

90
Prodo Labs human islet media
( A ) Proliferation of islets in the diseased (11 mM glucose, 50 µM HCT) and healthy (5.5 mM glucose, 10 nM HCT) conditions at the end of the culture as analysed by the percentage EdU-positive cells. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies. Differences between the static and the co-culture were evaluated by a two-tailed unpaired t-test, ns = not significant, ****p < 0.0001. ( B ) Multi-omics analysis on the effect of hyperglycemia vs. normoglycemia on liver-secreted proteins. Data from RNASeq (HepaRG/HHSteC spheroids) and proteomics (co-culture supernatants) were merged at the gene level. Point colour indicate significance of change (FDR<0.05 and p<0.05 for RNASeq and proteomics data, respectively). Gene names are marked for genes with RNASeq and proteomic log2 fold-changes > 1. Transcriptomics data is from three independent studies and proteomics data from four independent studies. ( C ) Secretion of IL-1R2 in the co-cultures over time. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies, total n = 8. ( D ) IL-1R2 stimulates cell proliferation at low dose (0.3 ng/mL) but not at the high dose (30 ng/mL) in islets mono-cultured in static condition in <t>Human</t> <t>Islet</t> <t>Maintenance</t> <t>Medium</t> (InSphero). Control, 0 ng/mL IL-1R2. Positive control, low hydrocortisone-normoglycemic (healthy) co-culture medium. Symbols represent individual islets. Differences to the control were evaluated by one-way ANOVA using Dunnett’s multiple comparisons post-hoc test, ns = not significant, ***p < 0.001.
Human Islet Media, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human islet media/product/Prodo Labs
Average 90 stars, based on 1 article reviews
human islet media - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

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( A ) Proliferation of islets in the diseased (11 mM glucose, 50 µM HCT) and healthy (5.5 mM glucose, 10 nM HCT) conditions at the end of the culture as analysed by the percentage EdU-positive cells. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies. Differences between the static and the co-culture were evaluated by a two-tailed unpaired t-test, ns = not significant, ****p < 0.0001. ( B ) Multi-omics analysis on the effect of hyperglycemia vs. normoglycemia on liver-secreted proteins. Data from RNASeq (HepaRG/HHSteC spheroids) and proteomics (co-culture supernatants) were merged at the gene level. Point colour indicate significance of change (FDR<0.05 and p<0.05 for RNASeq and proteomics data, respectively). Gene names are marked for genes with RNASeq and proteomic log2 fold-changes > 1. Transcriptomics data is from three independent studies and proteomics data from four independent studies. ( C ) Secretion of IL-1R2 in the co-cultures over time. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies, total n = 8. ( D ) IL-1R2 stimulates cell proliferation at low dose (0.3 ng/mL) but not at the high dose (30 ng/mL) in islets mono-cultured in static condition in Human Islet Maintenance Medium (InSphero). Control, 0 ng/mL IL-1R2. Positive control, low hydrocortisone-normoglycemic (healthy) co-culture medium. Symbols represent individual islets. Differences to the control were evaluated by one-way ANOVA using Dunnett’s multiple comparisons post-hoc test, ns = not significant, ***p < 0.001.

Journal: bioRxiv

Article Title: Diseased human pancreas and liver microphysiological system for preclinical diabetes research

doi: 10.1101/2023.07.03.547412

Figure Lengend Snippet: ( A ) Proliferation of islets in the diseased (11 mM glucose, 50 µM HCT) and healthy (5.5 mM glucose, 10 nM HCT) conditions at the end of the culture as analysed by the percentage EdU-positive cells. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies. Differences between the static and the co-culture were evaluated by a two-tailed unpaired t-test, ns = not significant, ****p < 0.0001. ( B ) Multi-omics analysis on the effect of hyperglycemia vs. normoglycemia on liver-secreted proteins. Data from RNASeq (HepaRG/HHSteC spheroids) and proteomics (co-culture supernatants) were merged at the gene level. Point colour indicate significance of change (FDR<0.05 and p<0.05 for RNASeq and proteomics data, respectively). Gene names are marked for genes with RNASeq and proteomic log2 fold-changes > 1. Transcriptomics data is from three independent studies and proteomics data from four independent studies. ( C ) Secretion of IL-1R2 in the co-cultures over time. Squares (study 2) and triangles (study 3) represent individual islets from two independent co-culture studies, total n = 8. ( D ) IL-1R2 stimulates cell proliferation at low dose (0.3 ng/mL) but not at the high dose (30 ng/mL) in islets mono-cultured in static condition in Human Islet Maintenance Medium (InSphero). Control, 0 ng/mL IL-1R2. Positive control, low hydrocortisone-normoglycemic (healthy) co-culture medium. Symbols represent individual islets. Differences to the control were evaluated by one-way ANOVA using Dunnett’s multiple comparisons post-hoc test, ns = not significant, ***p < 0.001.

Article Snippet: Medium was exchanged every 2-3 days with 70 µL of Human Islet Maintenance Medium (CS-07-005-02; InSphero).

Techniques: Co-Culture Assay, Two Tailed Test, Cell Culture, Positive Control